Fig. 4

An overview of co-expression modules identified from the lung cancer RNA-seq datasets used in this study. a Scale independence and b mean network connectivity for different soft-thresholding powers (β). A soft-thresholding power of 14 was selected to achieve maximal model fit. c Cluster dendrogram of the identified lncRNA-PEG co-expression modules. Each of the differential expressed lncRNAs and PCGs is represented by a tree leaf, and each of the six modules by a tree branch. The lower panel shows colors designated for each module. Note that the leaves presented in the color gray indicates unassigned lncRNAs and PCGs. d Module-trait weighted correlations and corresponding p values (in parenthesis) between the identified modules and clinical status (normal and tumor). The color scale on the right shows module-trait correlation from − 1 (green) to 1 (red), where green represents a perfect negative correlation, and red a perfect positive one