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Fig. 4 | Cancer Cell International

Fig. 4

From: Imiquimod inhibits growth and induces differentiation of myeloid leukemia cell lines

Fig. 4

Imiquimod leads to cell cycle arrest in some leukemic cell lines. a HL-60 cells with or without (control culture) treatment (Imiquimod at 10 µg/ml for 72 h) were permeabilized, stained with PI, and DNA contents were analyzed by flow cytometry. Gates of cells in different phases of the cell cycle are indicated. b The indicated cell lines, with or without Imiquimod treatment (10 µg/ml for 72 h) were permeabilized and stained with PI, and DNA contents were analyzed by flow cytometry. The percentage of cells in each phase of the cell cycle is shown. Data represent mean ± SD from two experiments. *P < 0.05, and **P < 0.01 with respect to control untreated cells

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