Loss of PIM1 correlates with progression and prognosis of salivary adenoid cystic carcinoma (SACC)

Table 2 Relationship between PIM1 and RUNX3 levels with the clinical characteristics

Variable	Patients (total = 97)		PIM1		p-value	RUNX3		p-value
Variable	Patients (total = 97)		Negative	Positive	p-value	Negative	Positive	p-value
Gender	Male	39	5	34	0.555	33	6	0.510
	Female	58	10	48		46	12
Age	< 52	52	9	43	0.589	41	11	0.479
	≥ 52	45	6	39		38	7
T-status	T1–2	33	14	19	0.000	20	13	0.000
	T3–4	64	1	63		59	5
Tumor location	Major salivary	36	6	30	0.801	29	7	0.863
	Minor salivary	61	9	52		50	11
Histological type	Cribriform	40	6	34	0.594	35	5	0.153
	Tubular	17	4	13		11	6
	Solid	40	5	35		33	7
Lymph node involvement	Yes	27	0	27	0.009	26	1	0.019
	No	70	15	55		53	17
Perineural invasion	Yes	57	1	56	0.000	52	5	0.003
	No	40	14	26		27	13
Distant metastasis	Yes	21	0	21	0.036	20	1	0.109
	No	76	15	61		59	17

ISSN: 1475-2867