Fig. 4From: Catalase down-regulation in cancer cells exposed to arsenic trioxide is involved in their increased sensitivity to a pro-oxidant treatmentHypothesis of molecular mechanisms leading to synergistic cytotoxic effects by arsenic trioxide and ascorbate/menadione association. ASH ascorbate, SDHA· semi-dehydro-ascorbyl radical, Q: quinone, SQ·: semiquinone radicalBack to article page