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Fig. 7 | Cancer Cell International

Fig. 7

From: The tyrosine kinase inhibitor nilotinib is more efficient than mitotane in decreasing cell viability in spheroids prepared from adrenocortical carcinoma cells

Fig. 7

Cell viability analysis of H295R cell line treated with imatinib (Ima) alone or with mitotane (Mit). MTS assay in monolayer cells after Ima treatment for 3 days (a) and (b) a combination of Ima and 10 μM Mit for 72 h; c MTS assay in spheroids after treatment with Ima or a combination of Ima and Mit; d phase-contrast photomicrography of spheroids after 72 h of treatment; e Confocal microscopy images of spheroids after 72 h of treatment (100 μm). The results are expressed as the mean ± SEM; ANOVA *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; n = 3-4

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