Table 2 Statistical values of correlation between LC50 values and relative mRNA levels of apoptotic proteins in leukemic samples
Anti-cancer drug | Symbol of gene | |||
|---|---|---|---|---|
p53 | Bax | Bcl-XL | Bcl-2 | |
Cytarabine | R = − 0.334 n = 36 p = 0.046 | − 0.16 36 0.350 | 0.011 36 0.950 | 0.130 34 0.463 |
Daunorubicin | − 0.445 26 0.022 | − 0.415 27 0.031 | − 0.235 26 0.246 | − 0.292 23 0.176 |
Etoposide | − 0.442 27 0.021 | − 0.374 28 0.049 | − 0.203 27 0.309 | − 0.269 27 0.174 |
Idarubicin | − 0.419 24 0.041 | − 0.444 24 0.029 | − 0.131 24 0.541 | − 0.194 23 0.374 |
Vincristine | − 0.192 36 0.263 | − 0.197 36 0.249 | − 0.006 36 0.969 | − 0.322 34 0.063 |