TY - JOUR AU - Goswamee, Priyodarshan AU - Pounardjian, Tamar AU - Giovannucci, David R. PY - 2018 DA - 2018/03/02 TI - Arachidonic acid-induced Ca2+ entry and migration in a neuroendocrine cancer cell line JO - Cancer Cell International SP - 30 VL - 18 IS - 1 AB - Store-operated Ca2+ entry (SOCE) has been implicated in the migration of some cancer cell lines. The canonical SOCE is defined as the Ca2+ entry that occurs in response to near-maximal depletion of Ca2+ within the endoplasmic reticulum. Alternatively, arachidonic acid (AA) has been shown to induce Ca2+ entry in a store-independent manner through Orai1/Orai3 hetero-multimeric channels. However, the role of this AA-induced Ca2+ entry pathway in cancer cell migration has not been adequately assessed. SN - 1475-2867 UR - https://doi.org/10.1186/s12935-018-0529-8 DO - 10.1186/s12935-018-0529-8 ID - Goswamee2018 ER -