Fig. 2

Effects of over-expression of E2F3a on the distribution of cell cycle phases and proliferation of 697. a E2F3a was significantly up-regulated after 24 h induction of Dox (0.5 μg/ml) in 697 (left) and REH (right) cells. b In 697 cells, Dox had no effect on the cell cycle phase fraction. c In 697 cells, over-expression of E2F3a resulted in decrease or increase in the fraction of cells in G0/G1, or S and G2/M phases respectively. d Over-expression of E2F3a led to accelerated proliferation. The standard errors of the means are shown (n = 3 experiments for each time point); independent-samples T test, *P < 0.05