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Fig. 4 | Cancer Cell International

Fig. 4

From: Transcription factor E2F3a regulates CASP8AP2 transcription and enhances sensitivity to chemotherapeutic drugs in acute lymphoblastic leukemia

Fig. 4

E2F3a over-expression enhanced the transcriptional activity of CASP8AP2. a E2F3a was up-regulated 24 h after transfection of pcDNA3-E2F3a in HCT116 cell. b, c In HCT116 and 697, relative luciferase activity of CASP8AP2-wild was higher than that of the 4 types of mutant promotor reporters when co-transfected with pcDNA3-E2F3a. The standard errors of the means are shown (n = 3 experiments for each mutant); independent-samples T test, *P < 0.05. d E2F3a over-expression resulted in up-regulation of CASP8AP2 in 697 cell

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Cancer Cell International

ISSN: 1475-2867

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