Transcription factor E2F3a regulates CASP8AP2 transcription and enhances sensitivity to chemotherapeutic drugs in acute lymphoblastic leukemia

Table 2 IC50 after treatment with VCR and DNR in leukemic cells over-expressing E2F3a

Cell lines	Drugs	E2F3a over-expression	IC50 (μg/ml)	P
697	VCR	Dox −	0.1313	< 0.001
	VCR	Dox +	0.0548	< 0.001
	DNR	Dox −	0. 0211	< 0.001
	DNR	Dox +	0.0075	< 0.001
REH	VCR	Dox −	0.0658	< 0.05
	VCR	Dox +	0.0211	< 0.05
	DNR	Dox −	0.0266	< 0.05
	DNR	Dox +	0.0108	< 0.05

ISSN: 1475-2867