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Fig. 5 | Cancer Cell International

Fig. 5

From: Overexpression of Rab11-FIP2 in colorectal cancer cells promotes tumor migration and angiogenesis through increasing secretion of PAI-1

Fig. 5

Pharmacological inhibition of PAI-1 resulted in the reduction of cell migration and colony formation, and the induction of apoptosis in CRC overexpressing Rab11-FIP2. a Targeting PAI-1 results in a reduction of cell migration in 15/FIP2 and 116/FIP2 cells. b Targeting PAI-1 results in a reduction of colony formation in 15/FIP2 and 116/FIP2 cells. c Targeting PAI-1 results in an induction of apoptosis in 15/FIP2 and 116/FIP2 cells. All results are from three independent experiments (*p < 0.05)

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