Fig. 2

Targeting relationship between miR-200c and XIST. a The relative mRNA expression level of miR-200 was detected using qPCR in sphere and parental cells. b The relative mRNA expression level of XIST was detected using qPCR in bladder cancer stem cell-like side population cells and parental cells. c The targeted binding sites of miR-200c and XIST. d The dual luciferase reporter assays showed that the relative luciferase activity of 5637 and T24 cells co-transfected with XIST-Wt and miR-200c was dramatically decreased compared with that of the control group. Data are presented as mean ± SD. **P < 0.01 vs. parental or control group