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Fig. 3 | Cancer Cell International

Fig. 3

From: LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells

Fig. 3

miR-200c mimics inhibited clone formation and self-renewal capacities in cancer stem cell-like side population cells. a qPCR assays were performed to assess the available 5637 and T24 bladder cancer stem cell-like side population cells transfected with miR-200c mimics and negative control (NC). b Cell clone formation assays demonstrated that the clone formation ability of 5637 and T24 cells was significantly decreased in the miR-200c mimics group compared to the NC group. c The self-renewal capacity of bladder cancer stem cell-like side population cells (magnification, 100×). d miR-200c mimics affected the expression of EMT-associated factors such as E-cadherin, vimentin and ZEB1 and ZEB2 proteins. Data are presented as mean ± SD. **P < 0.01 vs. mimics NC group

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