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Fig. 5 | Cancer Cell International

Fig. 5

From: MiR-544 promotes immune escape through downregulation of NCR1/NKp46 via targeting RUNX3 in liver cancer

Fig. 5

Effect of miR-544 on NCR1 expression. a The mRNA expression levels of miR-544 in control, IL-2, IL-2 + pre-NC, IL-2 + miR-544 mimic, IL-2 + miR-544 mimic + pcDNA and IL-2 + miR-544 mimic + pcDNA-RUNX3 groups. b The protein expression levels of NCR1 and RUNX3 in control, IL-2, IL-2 + pre-NC, IL-2 + miR-544 mimic, IL-2 + miR-544 mimic + pcDNA and IL-2 + miR-544 mimic + pcDNA-RUNX3 groups. c The mRNA expression of NCR1 in control, IL-2, IL-2 + pre-NC, IL-2 + miR-544 mimic, IL-2 + miR-544 mimic + pcDNA and IL-2 + miR-544 mimic + pcDNA-RUNX3 groups. d The percent of NKp46 + NK cells in control, IL-2, IL-2 + pre-NC, IL-2 + miR-544 mimic, IL-2 + miR-544 mimic + pcDNA and IL-2 + miR-544 mimic + pcDNA-RUNX3 groups using flow cytometry. *Refers to compare with the control group, P < 0.05. #Refers to compare with the IL-2 + pre-NC group, P < 0.05. &Refers to compare with the IL-2 + miR-544 mimic + pcDNA group, P < 0.05

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