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Table 1 Inhibitory concentration 50 (IC50)

From: Autophagy inhibition improves the cytotoxic effects of receptor tyrosine kinase inhibitors

Drug

IC50 at 24 h (mean ± SD) μM

Afatinib

7.7 ± 0.6

Sorafenib

12.4 ± 3.4

TP-0903

0.130 ± 0.009

  1. The concentration that inhibits cell viability for 50% was determine for each RTKi (Afatinib, Sorafenib and TP-0903). The mean values and standard deviations are indicated for 24 h treatment period
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Cancer Cell International

ISSN: 1475-2867

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