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Fig. 4 | Cancer Cell International

Fig. 4

From: Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer

Fig. 4

Transient silencing of ERβ induced ovarian cancer cell migration and invasion. a Transient knockdown of ERβ (siERβ) mRNA and protein expression in SKOV-3 cells by qPCR and immunoblot analysis respectively. b In vitro migration and invasion assays in SKOV-3 cells transient transfected with siRNA specifically targeting ERβ and control siRNA. Upper panel: representative images of migrating or invading cells. Lower panel: cell migration or invasion presented as percentage of control; n = 3; **p < 0.005

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