Fig. 9

Genistein, daidzein and ERB-041 suppressed FAK and PI3K/AKT/GSK signaling and modulated expression of cell cycle regulators or EMT markers in ovarian cancer cells. Immunoblot analysis on p-FAK, FAK, p-PI3K85, p-AKT, AKT, p-GSK, GSK, p21, cyclin D1, E-cadherin or vimentin in SKOV-3 cells treated with different doses of genistein (10 or 50 µM), daidzein (10 or 50 µM), ERB-041 (0.01, 0.1 or 10 µM) or DMSO (vehicle)