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Table 5 Heterogeneity test and publication analysis

From: Analysis of the role of rs2031920 and rs3813867 polymorphisms within the cytochrome P450 2E1 gene in the risk of squamous cell carcinoma

SNP

Comparisons

I2 (%)

P (heterogeneity)

F/R

P (Begg’s test)

P (Egger’s test)

rs2031920 (C/T)

Allele T vs. allele C

77.2

< 0.001

R

0.649

0.054

 

Carrier T vs. carrier C

58.9

0.001

R

0.449

0.077

 

TT vs. CC

38.3

0.066

F

0.276

0.242

 

CT vs. CC

82.1

< 0.001

R

0.544

0.544

 

CT + TT vs. CC

83.1

< 0.001

R

0.608

0.037

 

TT vs. CC + CT

57.4

0.002

R

0.685

0.207

rs3813867 (G/C)

Allele C vs. allele G

46.1

0.054

F

0.074

0.072

 

Carrier C vs. carrier G

28.4

0.183

F

0.107

0.150

 

CC vs. GG

45.4

0.103

F

0.707

0.651

 

GC vs. GG

52.4

0.026

R

0.107

0.230

 

GC + CC vs. GG

47.3

0.041

R

0.062

0.150

 

CC vs. GG + GC

43.6

0.115

F

1.000

0.732

rs2031920 + rs3813867 (c1/c2)

Allele c2 vs. allele c1

49.8

0.093

F

1.000

0.184

 

Carrier c2 vs. carrier c1

15.5

0.316

F

0.806

0.245

 

c2c2 vs. c1c1

0.0

0.671

F

0.296

0.269

 

c1c2 vs. c1c1

53.1

0.074

R

0.806

0.327

 

c1c2 + c2c2 vs. c1c1

46.3

0.083

F

0.764

0.227

 

c2c2 vs. c1c1 + c1c2

0.0

0.792

F

0.296

0.501

  1. SNP single nucleotide polymorphisms, F fixed, R random