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Table 1 Clinicopathological characteristics of study patients (n = 88)

From: APOBEC3B up-regulation independently predicts ovarian cancer prognosis: a cohort study

Variables

N

%

Age at diagnosis (years) Median (range)

51

26–74

Age (years)

  ≤ 50

41

46.6

  > 50

47

53.4

Overall survival (months)

 Median (range)

74.77

1.60–103.13

 Number of deaths

42

47.7

Disease free survival (months)

 Median (range)

67.65

0.80–103.13

 Number of recurrences

46

52.3

Menopause

 Yes

45

51.1

 No

43

48.9

Laterality

 Right side

23

26.1

 Left side

16

18.2

 Bilateral

49

55.7

Behavior

 Borderline

0

0

 Invasive

88

100

Histological subtype (%)

 Serous

59

67.0

 Non-serous

29

33.0

Histological grade (%)

 G1

8

9.1

 G2

21

23.9

 G3

37

42.0

 Missing

22

25.0

FIGO (%)

 I

25

28.4

 II

13

14.8

 III

45

51.1

 IV

5

5.7

Intravascular tumor thrombus (%)

 Yes

16

18.2

 No

69

78.4

 Missing

3

3.4

 Serum CA 125 (U/mL)

  < 35

11

12.5

  ≥ 35

63

71.6

 Missing

14

15.9

Serum CA 19-9 (U/mL)

  < 37

38

43.2

  ≥ 37

18

20.5

 Missing

32

36.4

Serum CEA (ng/mL)

 < 5

58

65.9

 ≥ 5

2

2.3

 Missing

28

31.8

Chemotherapy

 Yes

83

94.3

 Missing

5

5.7

Traditional Chinese medicine treatment

 Yes

18

20.5

 No

70

79.5

APOBEC3B

 −

8

9.1

 +

32

36.4

 ++

32

36.4

 +++

16

18.2

  1. APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B, CA 125 cancer antigen 125, CA 19-9 cancer antigen 19-9, CEA carcinoembryonic antigen, FIGO Federation of Gynecologists and Obstetricians