Table 3 Univariate and multivariate analyses of factors associated with overall survival

Univariate analyses

 Age (> 50 vs. ≤ 50)

1.10 (0.63–1.91)

0.734

1.18 (0.70–2.00)

0.537

 Histological subtype (serous vs. non-serous)

2.24 (1.12–4.47)

0.023

2.29 (1.18–4.43)

0.014

 FIGO stage (III/IV vs. I/II)

7.89 (3.53–17.60)

< 0.0001

9.40 (4.23–20.86)

<0.0001

 Histological grade (G2/G3 vs. G1)

1.36 (0.72, 2.54)

0.341

1.44 (0.79–2.63)

0.239

 Intravascular tumor thrombus (Yes vs. No)

2.27 (1.20–4.29)

0.012

2.00 (1.07–3.75)

0.030

 CA 125 (≥ 35 U/mL vs. < 35 U/mL)

5.45 (1.30–22.56)

0.019

5.90 (1.40–24.32)

0.014

 APOBEC3B (+++/++ vs. ±)

6.34 (2.80–14.38)

< 0.0001

5.18 (2.40–10.80)

< 0.0001

Multivariate analyses

 FIGO stage (III/IV vs. I/II)

7.89 (2.33–26.70)

0.001

9.75 (2.89–32.90)

< 0.0001

 APOBEC3B (+++/++ vs. ±)

5.18 (1.40–11.95)

0.003

4.23 (1.60–11.17)

0.004