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Fig. 5 | Cancer Cell International

Fig. 5

From: Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway

Fig. 5

VASP promotes GC cell proliferation by regulating the PI3K/AKT signaling pathway. a, b Protein levels of VASP in MGC-803 cells transfected with VASP knockdown plasmid (shVASP), VASP overexpressed plasmid (VASP) or pcDNA3.1 negative controls (Ctrl), as determined by Western-blot. c The mRNA levels of VASP in MGC-803 cells transfected with VASP knockdown plasmid (shVASP), VASP overexpressed plasmid (VASP) or pcDNA3.1 negative controls (Ctrl), as determined by qRT-PCR. d–f Activation of the PI3K/AKT signaling pathway in MGC-803 cells after transfection with VASP knockdown plasmid (shVASP), VASP overexpressed plasmid (VASP) or negative control plasmid (Ctrl). **P < 0.01, vs. Ctrl groups

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