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Fig. 4 | Cancer Cell International

Fig. 4

From: Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma

Fig. 4

Harmine induces PARP cleavage in NB cells. NB cell lines (SKNBE, KELLY, SKNAS, and SKNFI) were exposed to increasing concentrations of harmine, (0–100 μM) for 24 h and probed for PARP cleavage, an indicator of progressive apoptosis. Whole cell lysates were collected using RIPA lysis buffer and analyzed for PARP cleavage using Western blot. Data are representative of three independent experiments (n = 3)

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Cancer Cell International

ISSN: 1475-2867

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