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Fig. 1 | Cancer Cell International

Fig. 1

From: MiR-218 regulates epithelial–mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF

Fig. 1

miR-218 was down-regulated in CRC cell lines and tissue. a Compared to human normal colon epithelial cell line NCM460, miR-218 expression was significantly decreased in CRC cell lines, including SW620, SW480, HCT8, and HCT116. b Transfection with miR-218 mimics significantly increased its level in SW620 and HCT 116, compared to control groups N = 3. c Levels of miR-218 were obviously decreased in CRC patients’ samples, compared to adjacent normal tissues. N = 35. d In the late stage CRC tumors (N = 16), miR-218 was dramatically decreased compared to early stage CRC tumors (N = 19). *P < 0.05, ***P < 0.0001, t-test

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