Fig. 6
From: ETS1 is associated with cisplatin resistance through IKKα/NF-κB pathway in cell line MDA-MB-231
Down-regulation ETS1 improves the vivo sensitivity to DDP. a The average weight of mice were recorded every 3 days; b, c a month after initial cisplatin administration, the tumor volume and average weight receiving pCDNA-ETS1- or empty vector-transfected 231/DDP cells were recorded; d tumor volume was calculated every 3 days after cisplatin treatment; e a month after initial cisplatin administration, the tumor average weight receiving pCDNA-ETS1- or empty vector-transfected 231/DDP cells were recorded; *P < 0.05, **P < 0.01. f Tumors developed from PcDNA-ETS-transfected 231/DDP cells showed lower ETS1 protein levels by immunofluorescence staining; × 400