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Fig. 4 | Cancer Cell International

Fig. 4

From: Long noncoding RNA PVT1 modulates hepatocellular carcinoma cell proliferation and apoptosis by recruiting EZH2

Fig. 4

EZH2 protein stabilized MDM2 protein expression. a Co-IP assay indicated that EZH2 bound to MDM2. b QRT-PCR indicated that EZH2 mRNA in si-EZH2 group was lower than that in si-NC group. **P < 0.01, compared with si-NC group. c Western blot showed that MDM2 protein expression in si-EZH2 group was lower than that in si-NC group, while EZH2 protein expression in si-MDM2 group had no significant difference with that in si-NC group. d Western blot indicated that after added with 100 μg/mL CHX, si-EZH2 had greater inhibitory effect on MDM2 protein expression with the increase of time. f ELISA assay revealed that MDM2 protein expression in si-EZH2 group was lower than that in si-NC group with the increase of time after added with 100 μg/mL CHX. *P < 0.05, compared with si-NC group

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