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Table 2 Clinicopathological correlation of lncRNA PVT1 expression in human HCCs

From: Long noncoding RNA PVT1 modulates hepatocellular carcinoma cell proliferation and apoptosis by recruiting EZH2

Variables No. of cases PVT1 expressiona P value*
Low High
Age (years) 0.99
 ≥ 60 47 28 19
 < 60 74 44 30
Gender 0.801
 Female 65 38 27
 Male 56 34 22
AFP level (ng/mL) 0.082
 ≥ 400 60 31 29
 < 400 61 41 20
Tumor size (cm) 0.003
 ≥ 5 62 29 33
 < 5 59 43 16
Tumor number 0.003
 Single 54 40 14
 Multiple 67 32 35
Tumor grade 0.001
 G1 59 46 13
 G2 + G3 62 26 36
Tumor stage 0.010
 I + II 67 52 15
 III 54 20 34
  1. PVT1 plasmacytoma variant translocation 1, AFP alphafetoprotein
  2. * For analysis of correlation between PVT1 and clinical features, Pearson’s Chi square tests were used. Results were considered statistically significant at P < 0.05 with italics font
  3. a The average expression level was used as the cutoff. Low expression of PVT1 in 72 patients was classified as values below the fold change of 5.44 while high PVT1 expression in 49 patients was classified as values above the level