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Fig. 7 | Cancer Cell International

Fig. 7

From: CDA gene silencing regulated the proliferation and apoptosis of chronic myeloid leukemia K562 cells

Fig. 7

CDA gene silencing down-regulated BCL-2 and up-regulated p21, Bax, cleaved caspase-3/total caspase-3 and cleaved PARP/total PARP. a Protein bands of BCL-2, Bax, p21, cleaved caspase-3, total caspase-3, cleaved PARP, total PARP and GAPDH in each group; b protein expression of BCL-2, Bax, P21, cleaved caspase-3, total caspase-3, cleaved PARP, total PARP and GAPDH in each group; the data were expressed as mean ± standard deviation, n = 3, and One-Way ANOVA was used to analyzed the data. *Compared with the blank group, p < 0.05. CDA cytidine deaminase, BCL-2 B-cell lymphoma/leukemia-2, Bax BCL-2-associated X, PARP poly (ADP-ribose) polymeras, GAPDH glyceraldehyde-3-phosphate dehydrogenase

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