Table 2 Association between the two SNPs and risk of lung cancer and non-small cell lung cancer
Genotype | Controls (%) (593) | Lung cancer | Non-small cell lung cancer | ||||
|---|---|---|---|---|---|---|---|
Cases (%) (434) | ORa (95% CI) | P value | Cases (%)(331) | ORa (95% CI) | P value | ||
Rs4848320 | |||||||
 CC (ref) | 402 (67.8) | 291 (67.1) | 1.00 (ref) |  | 220 (66.5) | 1.00 (ref) |  |
 CT | 175 (29.5) | 131 (30.2) | 1.036 (0.788–1.362) | 0.800 | 101 (30.5) | 1.160 (0.787–1.427) | 0.703 |
 TT | 16 (2.7) | 12 (2.8) | 1.041 (0.482–2.247) | 0.918 | 10 (3.0) | 1.168 (0.515–2.647) | 0.710 |
 CT + TT vs CC |  |  | 1.036 (0.795–1.352) | 0.792 |  | 1.069 (0.801–1.426) | 0.653 |
 TT vs CT + CC |  |  | 1.030 (0.479–2.212) | 0.940 |  | 1.147 (0.509–2.586) | 0.741 |
Rs1110839 | |||||||
 TT (ref) | 250 (42.2) | 174 (40.1) | 1.00 (ref) |  | 134 (40.5) | 1.00 (ref) |  |
 TG | 274 (46.2) | 209 (48.2) | 1.083 (0.830–1.413) | 0.559 | 158 (47.7) | 1.068 (0.799–1.428) | 0.656 |
 GG | 69 (11.6) | 51 (11.8) | 1.079 (0.714–1.632) | 0.717 | 39 (11.8) | 1.066 (0.679–1.672) | 0.782 |
 TG + GG vs TT |  |  | 1.082 (0.839–1.394) | 0.543 |  | 1.068 (0.810–1.407) | 0.642 |
 GG vs TG + TT |  |  | 1.034 (0.702–1.525) | 0.864 |  | 1.029 (0.674–1.570) | 0.895 |