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Table 2 Association between the two SNPs and risk of lung cancer and non-small cell lung cancer

From: Polymorphism in lncRNA AC016683.6 and its interaction with smoking exposure on the susceptibility of lung cancer

Genotype Controls (%) (593) Lung cancer Non-small cell lung cancer
Cases (%) (434) ORa (95% CI) P value Cases (%)(331) ORa (95% CI) P value
Rs4848320
 CC (ref) 402 (67.8) 291 (67.1) 1.00 (ref)   220 (66.5) 1.00 (ref)  
 CT 175 (29.5) 131 (30.2) 1.036 (0.788–1.362) 0.800 101 (30.5) 1.160 (0.787–1.427) 0.703
 TT 16 (2.7) 12 (2.8) 1.041 (0.482–2.247) 0.918 10 (3.0) 1.168 (0.515–2.647) 0.710
 CT + TT vs CC    1.036 (0.795–1.352) 0.792   1.069 (0.801–1.426) 0.653
 TT vs CT + CC    1.030 (0.479–2.212) 0.940   1.147 (0.509–2.586) 0.741
Rs1110839
 TT (ref) 250 (42.2) 174 (40.1) 1.00 (ref)   134 (40.5) 1.00 (ref)  
 TG 274 (46.2) 209 (48.2) 1.083 (0.830–1.413) 0.559 158 (47.7) 1.068 (0.799–1.428) 0.656
 GG 69 (11.6) 51 (11.8) 1.079 (0.714–1.632) 0.717 39 (11.8) 1.066 (0.679–1.672) 0.782
 TG + GG vs TT    1.082 (0.839–1.394) 0.543   1.068 (0.810–1.407) 0.642
 GG vs TG + TT    1.034 (0.702–1.525) 0.864   1.029 (0.674–1.570) 0.895
  1. SNP single nucleotide polymorphism, OR odds ratio, CI confident interval
  2. ORa was adjusted by age, gender and smoking