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Table 6 Stratified analyses of association between the two SNPs and lung cancer risk by gender

From: Polymorphism in lncRNA AC016683.6 and its interaction with smoking exposure on the susceptibility of lung cancer

SNP Genotype Gender Controls (%) Cases (%) ORª (95% CI) P value
Rs4848320 CC Male 124 (68.9) 69 (62.2) 1.00 (ref)  
CT   51 (28.3) 37 (33.3) 1.334 (0.774–2.298) 0.299
TT   5 (2.8) 5 (4.5) 2.042 (0.500–8.333) 0.320
CT + TT vs CC     1.389 (0.821–2.350) 0.220
TT vs CT + CC     1.860 (0.461–7.498) 0.383
CC Female 278 (67.3) 222 (68.7) 1.00 (ref)  
CT   124 (30.0) 94 (29.1) 0.959 (0.695–1.323) 0.797
TT   11 (2.7) 7 (2.2) 0.824 (0.313–2.166) 0.694
CT + TT vs CC     0.948 (0.693–1.297) 0.737
TT vs CT + CC     0.835 (0.319–2.183) 0.713
Rs1110839 TT Male 79 (43.9) 32 (28.8) 1.00 (ref)  
TG   84 (46.7) 60 (54.1) 1.582 (0.908–2.757) 0.105
GG   17 (9.4) 19 (17.1) 3.096 (1.343–7.134) 0.008
TG + GG vs TT     1.804 (1.061–3.067) 0.029
GG vs TG + TT     2.376 (1.102–5.121) 0.027
TT Female 171 (41.4) 142 (44.0) 1.00 (ref)  
TG   190 (46.0) 149 (46.1) 0.957 (0.702–1.305) 0.783
GG   52 (12.6) 32 (9.9) 0.751 (0.457–1.233) 0.258
TG + GG vs TT     0.913 (0.680–1.228) 0.548
GG vs TG + TT     0.768 (0.481–1.228) 0.271
  1. SNP single nucleotide polymorphism, OR odds ratio, CI confident interval
  2. ORa was adjusted by age and smoking