Skip to main content

Table 7 Stratified analyses of association between the two SNPs and lung cancer risk by age

From: Polymorphism in lncRNA AC016683.6 and its interaction with smoking exposure on the susceptibility of lung cancer

SNP

Genotype

Age

Controls (%)

Cases (%)

ORª (95% CI)

P value

Rs4848320

CC

≤ 57

180 (68.2)

132 (69.5)

1.00 (ref)

 

CT

 

78 (29.5)

54 (28.4)

0.852 (0.548–1.324)

0.476

TT

 

6 (2.3)

4 (2.1)

1.323 (0.319–5.496)

0.700

CT + TT vs CC

   

0.876 (0.570–1.347)

0.547

TT vs CT + CC

   

1.385 (0.336–5.716)

0.652

CC

> 57

222 (67.5)

159 (65.2)

1.00 (ref)

 

CT

 

97 (29.5)

77 (31.6)

1.109 (0.768–1.602)

0.581

TT

 

15 (3.0)

8 (3.3)

1.214 (0.462–3.189)

0.694

CT + TT vs CC

   

1.119 (0.784–1.596)

0.537

TT vs CT + CC

   

1.175 (0.451–3.066)

0.741

Rs1110839

TT

≤ 57

115 (43.6)

85 (44.7)

1.00 (ref)

 

TG

 

123 (46.6)

86 (45.3)

0.943 (0.621–1.434)

0.784

GG

 

26 (9.8)

19 (10.0)

1.288 (0.633–2.620)

0.486

TG + GG vs TT

   

0.994 (0.666–1.484)

0.976

GG vs TG + TT

   

1.327 (0.674–2.612)

0.413

TT

> 57

135 (40.1)

89 (36.5)

1.00 (ref)

 

TG

 

151 (45.9)

123 (50.4)

1.299 (0.902–1.872)

0.160

GG

 

43 (13.1)

32 (13.1)

1.195 (0.698–2.048)

0.516

TG + GG vs TT

   

1.276 (0.902–1.806)

0.169

GG vs TG + TT

   

1.034 (0.628–1.703)

0.894

  1. SNP single nucleotide polymorphism, OR odds ratio, CI confident interval
  2. ORa was adjusted by gender and smoking