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Table 7 Stratified analyses of association between the two SNPs and lung cancer risk by age

From: Polymorphism in lncRNA AC016683.6 and its interaction with smoking exposure on the susceptibility of lung cancer

SNP Genotype Age Controls (%) Cases (%) ORª (95% CI) P value
Rs4848320 CC ≤ 57 180 (68.2) 132 (69.5) 1.00 (ref)  
CT   78 (29.5) 54 (28.4) 0.852 (0.548–1.324) 0.476
TT   6 (2.3) 4 (2.1) 1.323 (0.319–5.496) 0.700
CT + TT vs CC     0.876 (0.570–1.347) 0.547
TT vs CT + CC     1.385 (0.336–5.716) 0.652
CC > 57 222 (67.5) 159 (65.2) 1.00 (ref)  
CT   97 (29.5) 77 (31.6) 1.109 (0.768–1.602) 0.581
TT   15 (3.0) 8 (3.3) 1.214 (0.462–3.189) 0.694
CT + TT vs CC     1.119 (0.784–1.596) 0.537
TT vs CT + CC     1.175 (0.451–3.066) 0.741
Rs1110839 TT ≤ 57 115 (43.6) 85 (44.7) 1.00 (ref)  
TG   123 (46.6) 86 (45.3) 0.943 (0.621–1.434) 0.784
GG   26 (9.8) 19 (10.0) 1.288 (0.633–2.620) 0.486
TG + GG vs TT     0.994 (0.666–1.484) 0.976
GG vs TG + TT     1.327 (0.674–2.612) 0.413
TT > 57 135 (40.1) 89 (36.5) 1.00 (ref)  
TG   151 (45.9) 123 (50.4) 1.299 (0.902–1.872) 0.160
GG   43 (13.1) 32 (13.1) 1.195 (0.698–2.048) 0.516
TG + GG vs TT     1.276 (0.902–1.806) 0.169
GG vs TG + TT     1.034 (0.628–1.703) 0.894
  1. SNP single nucleotide polymorphism, OR odds ratio, CI confident interval
  2. ORa was adjusted by gender and smoking