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Table 8 Crossover analysis of interaction between rs4848320, rs1110839 risk genotypes and smoking exposure

From: Polymorphism in lncRNA AC016683.6 and its interaction with smoking exposure on the susceptibility of lung cancer

SNPs Genotype Smoking exposure Controls (%) Cases (%) ORa (95% CI) P value
Rs4848320 CC Never 314 (53.0) 233 (53.7) 1 (ref)  
CT + TT Never 161 (27.2) 105 (24.2) 0.875 (0.648–1.182) 0.384
CC Ever 88 (14.8) 58 (13.4) 1.129 (0.738–1.728) 0.576
CT + TT Ever 30 (5.1) 85 (31.8) 2.218 (1.272–3.869) 0.005
Rs1110839 TT Never 200 (33.7) 144 (33.2) 1 (ref)  
TG + GG Never 275 (46.4) 194 (44.7) 0.968 (0.729–1.286) 0.822
TT Ever 50 (8.4) 30 (6.9) 1.043 (0.611–1.782) 0.877
TG + GG Ever 68 (11.5) 66 (15.2) 1.755 (1.108–2.781) 0.017
  1. CI confidence interval, OR odds ratio
  2. ORa was adjusted by age, gender