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Table 1 Correlation between B7-H4 expression and clinicopathological parameters in TNBC

From: B7-H4 overexpression contributes to poor prognosis and drug-resistance in triple-negative breast cancer

Parameters n B7-H4 expression p B7-H4 intensity p
Low High Weak Moderate Strong
Age
 ≤ 50 30 5 25 0.612 4 14 12 0.664
 > 50 29 5 24 3 11 15
Menopausal
 Premenopausal 30 6 24 0.425 5 13 12 0.440
 Postmenopausal 29 5 24 2 12 15
Tumor histology
 IDC 45 10 35 0.051 7 21 17 0.059
 Non-IDC 14 1 13 0 4 10
Tumor size
 ≤ 2 4 3 1 0.055 1 2 1 0.113
 2–5 42 7 35 6 20 16
 > 5 13 0 13 0 3 10
Tumor grade
 I–II 26 9 17 0.002 7 12 7 0.004
 III 33 1 32 0 13 20
TNM stage
 I 3 3 0 0.006 1 2 0 0.003
 II 41 7 34 6 22 13
 III 15 0 15 0 1 14
Metastasis
 Yes 21 9 12 0.001 7 10 4 0.001
 No 38 2 36 0 15 23
Ki-67
 + 8 4 4 0.053 3 3 2 0.062
 ++ 29 6 23 4 13 12
 +++ 22 2 20 2 7 13
AR
 − 38 3 35 0.007 2 11 25 0.003
 + 21 9 12 6 10 5
Recurrence
 Yes 25 9 16 0.003 7 10 8 0.002
 No 34 4 30 2 13 19
  1. Numbers in italic indicate statistical significance