Fig. 6

5-FU drug-resistance assays. a The dose–effect curves were drawn based on the CCK-8 assay. All curves presented a right shift in the CM group compared with the control group. b Apoptosis analysis. After treatment with 5-FU (100 ng/mL) for 24 h, more apoptotic cells (especially in the early stage) were observed in all three CM-treated groups. c Expression level of PARP, cleaved PARP, Bak, Bax and cleaved caspase 3, after treatment with 5-FU for 72 h. d Expression level of E-cadherin, vimentin, snail and slug after treatment with CM for 72 h