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Fig. 2 | Cancer Cell International

Fig. 2

From: Circ-ZEB1.33 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6

Fig. 2

Tissue and serum circ-ZEB1.33 can serve as a biomarker in diagnosis and prediction the prognosis of HCC. The comparison between the expression level of circ-ZEB1.33 in tumor tissues and patients’ serum were presented in a and b respectively. c, d The transcription and protein expression of CDK6 in tumor tissue circ-ZEB1.33 High and low subgroup were determined by real-time PCR and IHC respectively. For integrated optical intensity (IOD) value estimation, the random five figures of each slide were analyzed by using image J. e, f the linear correlation between the transcription of CDK6 and circ-ZEB1.33 or miR-200a-3p in HCC tissues were analyzed. g, h the survival comparisons according to the expression of circ-ZEB1.33 in the tumor (g) and serum (h) were performed by using Kaplan–Meier curve. The data were presented as mean ± SD, *P < 0.05, **P < 0.01, by Student’s t-test

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