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Table 1 Correlation of positive and negative expressions of JAK2, STAT3 and VEGF with clinicopathologic characteristics of NPC

From: Clinicopathologic and prognostic significance of VEGF, JAK2 and STAT3 in patients with nasopharyngeal carcinoma

Clinicopathologic characteristics Case JAK2 χ2 P STAT3 χ2 P VEGF χ2 P
Positive Negative Positive Negative Positive Negative
Gender
 Male 62 38 24 0.295 0.587 44 18 0.220 0.639 44 18 5.459 0.622
 Female 41 24 17    29 12    37 4   
Age (year)
 < 50 47 32 15 0.274 0.600 34 13 1.862 0.172 36 11 1.026 0.311
 ≥ 50 56 30 26    39 17    45 11   
T stage
 T1-2 22 12 10 0.373 0.042 11 11 3.311 0.015 15 7 1.822 0.002
 T3-4 81 50 31    62 19    66 15   
LNM
 Yes 60 41 19 3.974 0.046 48 12 0.421 0.016 51 9 3.460 0.043
 No 43 21 22    25 18    30 13   
N stage
 N0 28 13 15 0.704 0.015 25 3 0.317 0.033 26 2 4.627 0.031
 N1-3 75 49 26    48 27    55 20   
Differentiation type
 Differentiated 72 46 26 1.363 0.243 50 22 0.211 0.646 56 16 0.039 0.843
 Undifferentiated 31 16 15    23 8    25 6   
Clinical stage
 I–II 48 22 26 5.655 0.017 29 19 0.771 0.038 29 19 13.942 <0.001
 III–IV 55 40 15    44 11    52 3   
Smoking history
 Yes 32 23 9 0.571 0.450 25 7 4.099 0.053 27 5 0.909 0.340
 No 71 39 32    48 23    54 17   
Family history
 Yes 19 11 8 0.051 0.821 13 6 0.672 0.412 14 5 1.449 0.229
 No 84 51 33    60 24    67 17   
  1. NPC nasopharyngeal carcinoma, LNM lymph node metastasis, JAK2 Janus kinase 2, STAT3 Signal transducer and activator of transcription-3, VEGF Vascular endothelial growth factor, T stage, lymph node metastasis, N stage and clinical stage, all P < 0.05