Table 2 The pooled associations between Gal-1 expression and the prognosis of cancerous patients (OS)
From: Prognostic significance of galectin-1 expression in patients with cancer: a meta-analysis
Outcome subgroup | No. of studies | No. of patients | HR (95% CI) | P value | Model | Heterogeneity | |
|---|---|---|---|---|---|---|---|
I2 (%) | P | ||||||
All | 18 | 2674 | 1.79 (1.54–2.08) | < 0.001 | Random | 43.6 | 0.025 |
Ethnicity | |||||||
Asian | 12 | 1734 | 1.96 (1.60–2.42) | < 0.001 | Random | 50.5 | 0.023 |
Caucasian | 6 | 940 | 1.42 (1.21–1.66) | < 0.001 | Fixed | 0.00 | 0.716 |
Tumor type | |||||||
Digestive system | 7 | 1268 | 1.94 (1.64–2.30) | < 0.001 | Fixed | 20.1 | 0.276 |
NOT digestive system | 11 | 1406 | 1.61 (1.33–1.94) | < 0.001 | Random | 42.5 | 0.066 |
Analysis type | |||||||
Univariate | 18 | 2674 | 1.79 (1.54–2.09) | < 0.001 | Random | 50.0 | 0.008 |
Multivariate | 4 | 765 | 1.93 (1.60–2.32) | < 0.001 | Fixed | 0.00 | 0.572 |
HR obtained method | |||||||
Reported in text | 7 | 1302 | 1.77 (1.42–2.20) | < 0.001 | Random | 49.2 | 0.066 |
Data extrapolated | 11 | 1372 | 1.77 (1.42–2.20) | < 0.001 | Random | 47.6 | 0.039 |