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Fig. 4 | Cancer Cell International

Fig. 4

From: MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma

Fig. 4

a Detection of differences in PTEN expression in normal osteoblasts (hFOB 1.19) and osteosarcoma cell lines (MG-63, 143B, Saos-2 and UMR-106). b Detection of differences in PTEN expression between osteosarcoma and para-carcinoma tissues by qRT-PCR. After overexpression of PTEN in MG-63 (c) and 143B cells (d), proliferation is significantly decreased. e There is a negative correlation between miR-524 and PTEN expression levels in osteosarcoma tissues (n = 20) (***P < 0.001, **P < 0.01, *P < 0.05)

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