Fig. 3

TAZ modulates HepG2 cell proliferation and migration. a, b Transwell assays were used to observe HepG2 cell migration. c–e Protein was isolated from HepG2 cell, and western blotting was conducted to analyze the expression of CXCR4 and CXCR7, which are key factors involved in the cancer cell migratory response. f, g EdU assays were performed to verify the functional role of TAZ in HepG2 cell growth. The number of EdU-positive cells was recorded. h–j To assess cellular response to IL-2 treatment and TAZ knockdown, protein was collected, and western blotting was used to analyze the expression of Cyclin D1 and Cyclin E. *P < 0.05 vs. control (Ctrl) group; ^#P < 0.05 vs. IL-2 group