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Table 2 Gene ontology term enrichment of differentially expressed genes in the A549 and U87-MG SOX2OT knocked down cells

From: SOX2OT knockdown derived changes in mitotic regulatory gene network of cancer cells

A549 cell line U87-MG cell line
GO-ID p-value Corr p-value X Description GO-ID p-value Corr p-value X Description
9987 1.83E−05 9.26E−03 61 Cellular process 32502 4.68e−02 3.40e−01 96 Developmental process
44085 1.03E−04 1.06E−02 21 Cellular component biogenesis 6807 2.55e−03 3.19e−01 76 Nitrogen compound metabolic process
7049 6.16E−05 9.26E−03 17 Cell cycle 6950 2.55e−02 3.19e−01 58 Response to stress
22402 4.46E−04 1.90E−02 14 Cell cycle process 30154 4.98e−02 3.40e−01 53 Cell differentiation
48519 8.18E−05 9.85E−03 13 Negative regulation of biological process 42127 5.77e−03 3.19e−01 34 Regulation of cell proliferation
43933 2.12E−03 4.64E−02 13 Macromolecular complex subunit organization 6629 3.47e−02 3.40e−01 30 Lipid metabolic process
278 1.47E−04 1.18E−02 11 Mitotic cell cycle 6811 4.39e−02 3.40e−01 27 Ion transport
51301 5.24E−04 1.95E−02 11 Cell division 22008 2.10e−02 3.19e−01 25 Neurogenesis
22403 2.29E−03 4.73E−02 11 Cell cycle phase 48699 1.72e−02 3.19e−01 24 Generation of neurons
10605 3.55E−04 1.74E−02 10 Negative regulation of macromolecule metabolic process 8285 8.58e−03 3.19e−01 18 Negative regulation of cell proliferation
45892 6.13E−05 9.26E−03 9 Negative regulation of transcription, DNA-dependent 55086 2.43E−02 3.19E−01 14 Nucleobase, nucleoside and nucleotide metabolic process
45934 3.61E−04 1.74E−02 9 Negative regulation of nucleic acid metabolic process 6954 3.08e−02 3.40e−01 14 Inflammatory response
51172 3.61E−04 1.74E−02 9 Negative regulation of nitrogen compound metabolic process 7420 4.63e−02 3.40e−01 13 Brain development
6260 5.07E−04 1.95E−02 7 DNA replication 6916 3.19E−02 3.40E−01 10 Anti-apoptosis
9628 1.19E−03 3.18E−02 7 Response to abiotic stimulus 6260 4.82e−02 3.40e−01 9 DNA replication
6261 2.03E−03 4.59E−02 5 DNA-dependent DNA replication 1525 4.03E−02 3.40E−01 8 Angiogenesis
10688 2.93E−04 1.74E−02 2 Negative regulation of ribosomal protein gene transcription 51325 1.84e−02 3.19e−01 7 Interphase
30837 2.00E−03 4.59E−02 2 Negative regulation of actin filament polymerization 7265 2.41e−02 3.19e−01 7 Ras protein signal transduction
32272 2.00E−03 4.59E−02 2 Negative regulation of protein polymerization 82 4.27e−02 3.40e−01 4 G1/s transition of mitotic cell cycle
8154 2.00E−03 4.59E−02 2 Actin polymerization or depolymerization 48048 8.49e−03 3.19e−01 3 Embryonic eye morphogenesis
  1. X: the number of genes in enriched GO term, corr p-value: FDR corrected p-value