Fig. 6

MiR-876-5p inhibits vimentin expression and suppresses hepatic metastasis of HNSCC cells in vivo. a, b Tumor volume was not significantly different between the agomir-876-5p and negative control groups. Each group contains seven nude mice. c Histological and immunohistochemical analysis of Ki-67 and vimentin. Scale bar, 50 μm. d Representative histological images show tumor metastases in the liver of nude mice. e The number of micrometastases on the liver surface was calculated. Each group contains three nude mice. *P < 0.05, **P < 0.01, ***P < 0.001