Fig. 4
From: Effect of dietary components on miRNA and colorectal carcinogenesis
Dietary modulation of microRNAs in colorectal cancer. Several dietary components show chemo-preventive and therapeutic potential in CRC pathogenesis through the modulation of miRNAs in difference signaling pathways. Line arrows indicate up-regulation; blunted lines with flat heads indicate inhibition, while dotted lines indicate multiple steps. CSF-1 Colony stimulating factor 1, E2F3 E2F transcription factor 3, HNRPH1 heterogeneous nuclear ribonucleoprotein H1, JMJDIA Jumonji domain-containing protein 1A, NFAT5 nuclear factor of activated T-cells 5, SIRT1 Sirtuin (silent mating type information regulation 2 homolog) 1, SMAD3 mother against decapentaplegic homolog 3, TGFβ1 transforming growth factor beta 1