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Table 1 BC094916 mRNA expression decreased in TACI-IgG-regulated plasma cells

From: BC094916 suppressed SP 2/0 xenograft tumor by down-regulating Creb1 and Bcl2 transcription

Gene symbol Gene description Fold change Regulation
Prdm1 PR domain containing 1, with ZNF domain 15.73 Up
Xbp1 X-box binding protein 1 4.88 Up
Pax5 paired box gene 5 0.19 Down
Bcl6 B cell leukemia/lymphoma 6 0.20 Down
BC094916 cDNA sequence BC094916 0.14 Down
  1. Three lupus-prone mice per group were injected i.p. with 5 mg/kg TACI-IgG or control IgG at 1, 2, 3, and 4 weeks (two times per week) after mice reached 6 months of age. On day 4 after therapy, mice were euthanized and B cells were separated from the spleen by B220 microbeads. The transcripts in B cells were determined by Affymetrix Microarrays. The fold change of the transcripts in TACI-IgG treatment to those in IgG group is shown