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Fig. 5 | Cancer Cell International

Fig. 5

From: Long noncoding RNA ROR promotes breast cancer by regulating the TGF-β pathway

Fig. 5

Linc-ROR modulates the TGF-β signaling pathway. a Western blot probing TGF-β, Smad2 and α-SMA in the MCF-7 cells. The cells were transfected with si-ROR or si-nc. GAPDH was blotted as an internal reference. b Quantitative comparison of the expression levels of TGF-β, Smad2 and α-SMA. The protein expression levels in the MCF-7 cells transfected with si-nc were normalized to 1. The cells transfected with si-ROR showed reduced expression of all three proteins. c, d Comparison of the protein expression levels of TGF-β, Smad2 and α-SMA in the MDA-MB-231 cells. The panels were arranged as a, b. Data were Mean ± SD derived from three independent experiments. *p < 0.05 vs the control

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