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Fig. 1 | Cancer Cell International

Fig. 1

From: LncRNA SNHG5 promotes the progression of osteosarcoma by sponging the miR-212-3p/SGK3 axis

Fig. 1

LncRNA SNHG5 regulates the proliferation and colony formation of osteosarcoma. a, b The microarray data obtained from the GEO database (GSE70415, GSE49003) to investigate the clinical relevance of lncRNA SNHG5 in osteosarcoma. Red or green color in heatmap separately shows high or low expression, according to the color bar in logarithmic scale shown above the heatmap. c Kaplan–Meier survival curves for OS patients with SNHG5 expression based on data of GSE39058. df qPCR detected the expression of SNHG5 in OS cells and the successful establishment of the SNHG5 overexpression and knockdown cell models. g, h The MTT assay shows that cell proliferation is inhibited in the si-SNHG5 group and is enhanced in the SNHG5 overexpression model. i The clony numbers decreased in the knockdown model and increased in the overexpression cell models. n = 3, **P < 0.01, ***P < 0.001 vs. control/vector

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