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Fig. 6 | Cancer Cell International

Fig. 6

From: LncRNA DLX6-AS1 promoted cancer cell proliferation and invasion by attenuating the endogenous function of miR-181b in pancreatic cancer

Fig. 6

Knockdown of DLX6-AS1 inhibited in vivo tumor growth in nude mice. a The tumor volume at 25, 30 and 35 days following tumor cells injection was significantly lower in shDLX6-AS1 group than that in shNC group. b The weight of dissected tumors in shDLX6-AS1 group was lower than that in shNC group. c The number of metastatic nodules in the lung from shDLX6-AS1 group was reduced compared to that in shNC group. The expression of d DLX6-AS1 and e miR-181b in dissected tumor tissues from shNC group and shDLX6-AS1 group were determined qRT-PCR. f The mRNA and g protein expression of ZEB2, E-cadherin, vimentin and N-cadherin in the dissected tissues were determined by qRT-PCR and western blot, respectively. *P < 0.05, **P < 0.01 and ***P < 0.001

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