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Fig. 3 | Cancer Cell International

Fig. 3

From: A drug screening assay on cancer cells chronically adapted to acidosis

Fig. 3

RNAseq data analysis. a A network graph visualizing the results from the community analysis. Edge (line) direction is represented by color with edges originating from a node inheriting that nodes color. Edges between community nodes (large points) indicate that the GO terms representing the nodes are each other’s ancestors or offspring dependent on the direction of the edge. Edges between term nodes (small points) and community nodes indicate the terms inclusion in that community. b A heatmap representing gene expression profiles in the detected communities. Communities are indicated by the color bar on the right side of the heatmap. Expression scaled to [0, 1] indicates the regularized log transformed expression values scaled between 0 and 1. c Gene expression profiles for selected terms in a subset of the detected communities for parental and acid adapted cells. Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (APPEP); generation of precursor metabolites and energy (GPME); somatic recombination of immunoglobulin genes involved in immune response (SRIGIIR)

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