Variables | Three years’ OS | |||
---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
HR (95% CI) | p-value | Adjusted HR (95% CI)a | p-value | |
Gender (male) | 1.787 (0.927–3.445) | 0.083 | – | – |
Age (≥ 60 years) | 1.017 (0.663–1.559) | 0.940 | – | – |
Tobacoo (yes) | 1.093 (0.727–1.643) | 0.670 | – | – |
Alcohol (yes) | 1.065 (0.703–1.614) | 0.767 | – | – |
Hypertension (yes) | 1.102 (0.482–2.522) | 0.818 | – | – |
Diabetes (yes) | 20.837 (0.042–10283.099) | 0.337 | – | – |
Tumor stage (III) | 1.460 (0.945–2.256) | 0.088 | – | – |
Depth of invasion (T3) | 2.523 (1.366–4.661) | 0.003 | 3.622 (1.591–8.242) | 0.002 |
Lympth node (yes) | 1.086 (0.717–1.645) | 0.098 | – | – |
Differentiation (poor) | 2.041 (1.008–4.131) | 0.047 | 1.579 (0.641–3.889) | 0.321 |
Tumor size (≥ 4 cm) | 1.413 (0.910–2.193) | 0.124 | – | – |
Radio-chemotherapy (yes) | 1.444 (0.812–2.566) | 0.211 | – | – |
NLR (≥ 2.1) | 1.495 (0.967–2.311) | 0.070 | – | – |
PLR (≥ 145.9) | 1.640 (1.085–2.479) | 0.019 | 1.964 (1.129–3.415) | 0.017 |
LMR (< 2.3) | 2.066 (1.166–3.663) | 0.013 | 1.445 (0.669–3.115) | 0.349 |
dNLR (≥ 4.3) | 2.387 (1.515–3.761) | < 0.001 | 2.338 (1.626–5.308) | < 0.001 |
Fib (≥ 3.2 mg/dL) | 1.886 (1.242–2.866) | 0.003 | 2.148 (1.229–3.753) | 0.007 |
Alb (< 38.2 g/L) | 1.969 (1.266–3.058) | 0.003 | 2.398 (1.342–4.273) | 0.003 |
AFR (< 9.3) | 1.953 (1.175–3.247) | 0.010 | 2.381 (1.152–4.926) | 0.019 |