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Table 2 The main clinicopathologic features of patients and their distribution in the eligible studies

From: Prognostic value of Kindlin-2 expression in patients with solid tumors: a meta-analysis

Study (Author and year) n Age (years or numbers): [mean or median (range)] (cut-off: low/high) Sex (M/F) Histological differentiation (I/II/III) Tumor size (cm) (cut-off) (low/high) Tumor category (grade) Lymphatic invasion () Vascular invasion (low/high) Metastasis () Staging method Stage (cut-off) Other therapy (no/yes)
Yoshida et al. 2017 (I) [14] 79 65 (mean) (41–85) (65):39/40 51/28 9/63/7 NR NR 19/60 32/47 NR NR NR C: 9/70
R: 68/11
Zhan et al. 2015 [15] 31 NR NR NR NR NR NR NR NR NR NR NR
Mahawithitwong et al. 2013 [16] 95 65 (mean) (36–86)
(65): 52/43
58/37 10/33/52 NR (T1/2/3/4) 9/3/82/1 34/61* 38/57 NR UICC NR C: 10/85
R: 78/17
Cao et al. 2015 (II) [17] 110 (58): 55/55 80/30 33/67/10 (3, 5) 32/45/11 (T1, 2/3, 4) 7/103 57/53 NR NR TNM (IIB/IIIA) 59/51 99/12
Cao et al. 2015 (III)[17] 147 (58): 79/68 113/34 23/109/15 (3, 5) 38/71/36 (T1, 2/3, 4) 20/127 64/83 NR NR TNM (IIB/IIIA) 70/77 104/43
Wu et al. 2017 [18] 203 (65): 109/94 165/38 (Low/high) 96/107* (3) 140/63 NR NR NR NR TNM (I/II) 8/115* NR
Papachristou et al. 2008 [19] 60 54 (mean) (21–85) 34/26 20/29/11* (8) 23/37 NR NR NR NR NR NR NR
Ge et al. 2015 [20] 72 (53): 35/37 60/12 NR (5) 29/43* NR NR Cap: 44/28*
Mic: 49/23*
NR TNM (II/III) 41/31 NR
Lin et al. 2017 [21] 127 (60): 111/16 17/110 NR (3) 10/117 NR NR Cap: 40/87
Mic: 66/61*
9/115* NR (II/III) 11/116 NR
Ning et al. 2017 [22] 100 (18): 40/60 68/32 (Low/high) 15/85* NR NR NR NR 60/40* NR NR RC: 50/50*
Ou et al. 2016 [23] 188 39 (mean)
(39): 98/90*
103/85 NR NR NR NR NR NR NR (II/III) 85/103* NR
Ren et al. 2014 [24] 113 (50): 28/85* −/113 (Low/high)
26/87*
NR NR NR NR 49/34 FIGO (I/II/III/IV) 9/13/73/10 RC: 21/68
Shen et al. 2012 [25] 40 67 (mean) (47–93)
(60): 14/26
30/10 4/8/28 NR (T1, 2/3, 4) 8/32* N1/2/3 21/10/9* NR 37/3 Pathologic (II/III) 8/32* NR
Li et al. 2017 [26] 109 (60):62/47 67/42 36/41/32* NR (Tx/1/2/34) 4/68/20/17 Nx/0/1 2/99/8* NR NR AJCC (II/III) 70/39 NR
Yan et al. 2016 [27] 336 (65):177/159 240/96 NR (4) 176/160 (T1, 2/3, 4) 167/169 202/134 NR 269/67* TNM (II/III) 124/212* NR
  1. (I) This article (Yoshida [14]) was listed two cohort study because the sample types contains cancer tissue and startle cell. (II) and (III) This article (Cao [17]) included patients from generation dataset (II) and validation dataset (III)
  2. n: number of patients; NR: no report; Cap: capillary invasion; Mic: microvascular invasion; C: chemotherapy; R: radiotherapy; RC: response for chemotherapy
  3. *Means that Kindlin-2 expression was reported to have a significant relation with the variable in the study