Table 1 Characteristics of patients with metastatic colorectal cancer
From: Predictive role of UCA1-containing exosomes in cetuximab-resistant colorectal cancer
| Â | All patients n (%) | Responders n (%) | Non-responders n (%) | p-value* |
|---|---|---|---|---|
Total number | 53 (100) | 30 (56.6) | 23 (43.4) | Â |
Sex | NS | |||
 Male | 31 (58.5) | 18 (60.0) | 13 (56.5) |  |
 Female | 22 (41.5) | 12 (40.0) | 10 (43.5) |  |
Age | NS | |||
 ≤ 70 | 38 (71.7) | 25 (83.3) | 13 (56.5) |  |
 > 70 | 15 (28.3) | 5 (16.7) | 10 (43.5) |  |
Median (range) | 56 (31–82) | 51.5 (31–82) | 59 (37–77) |  |
Histologic grade | NS | |||
 Low gradea | 45 (84.9) | 27 (90.0) | 18 (78.3) |  |
 High gradeb | 8 (15.1) | 3 (10.0) | 5 (21.7) |  |
Metastatic pattern | NS | |||
 Metachronous | 14 (26.4) | 7 (23.3) | 7 (30.4) |  |
 Synchronous | 39 (73.6) | 23 (76.7) | 16 (69.6) |  |
Primary tumor site | NS | |||
 Colon | 32 (60.4) | 18 (60.0) | 14 (60.9) |  |
 Rectum | 21 (39.6) | 12 (40.0) | 9 (39.1) |  |
Metastatic site | ||||
 Liver | 37 | 20 | 17 | NS |
 Lung | 21 | 11 | 10 |  |
 Other | 22 | 9 | 13 |  |
Number of metastatic site | NS | |||
 1 | 30 (56.7) | 19 (63.3) | 11 (47.8) |  |
 > 1 | 23 (43.4) | 11 (36.7) | 12 (52.2) |  |
Treatment regimen | NS | |||
 First line | 39 (73.6) | 23 (76.7) | 16 (69.6) |  |
 Third line | 14 (26.4) | 7 (23.3) | 7 (30.4) |  |