Table 1 Expression of CLDN2 and clinicopathological characteristics in OS patients
Item | N | CLDN2 (high) | CLDN2-negative (low) | P |
|---|---|---|---|---|
Tumor tissue | 27 | 9 | 18 | < 0.001* |
Normal | 10 | 8 | 2 | |
Age (years) | ||||
≤ 19 | 15 | 5 | 10 | 0.871 |
> 19 | 12 | 4 | 7 | |
Gender | ||||
Male | 16 | 5 | 11 | 1.000 |
Female | 11 | 4 | 7 | |
Stage | ||||
IA–IIA | 10 | 3 | 7 | 0.726 |
IIB–III | 17 | 6 | 11 | |
Response to chemotherapy | ||||
Poor | 9 | 2 | 7 | 0.642 |
Good | 7 | 2 | 5 | |
NA (n = 8) | 11 | |||
Pulmonary metastasis | ||||
+ | 21 | 6 | 15 | < 0.001* |
− | 6 | 3 | 3 | |